How to Test Your NAD+ Levels at Home (DoNotAge vs. Jinfiniti Compared)

Two test options, one clear recommendation, and what your results actually mean.

If you're spending $200/month on NAD+ precursors, you should know whether they're working. Feelings are subjective. Lab numbers are not. Testing before and after supplementation is the only way to know if you're getting your money's worth.

DoNotAge NAD+ test vs. Jinfiniti NAD+ test

DoNotAge sells an at-home NAD+ test kit on their site. You prick your finger, fill a blood spot card, and mail it to their lab. Results come back in about two weeks. It measures NAD+ in your blood sample.

Jinfiniti offers an intracellular NAD+ test that measures levels inside your cells (specifically, inside red blood cells) rather than just in blood serum. Intracellular measurement is generally considered more clinically relevant because NAD+ functions inside cells, not floating in your bloodstream.

Which NAD+ test should you buy?

If you're using DoNotAge products, their test kit is convenient and creates a consistent baseline for their own clinical data. If you want the more granular measurement, Jinfiniti's intracellular test gives you a richer picture.

Pick based on what you plan to do with the data. If you just want to confirm that your NMN supplementation is raising NAD+, either test works. If you want to optimize dosing or compare your levels against the clinical literature (which mostly references intracellular levels), go with Jinfiniti.

Both tests run around $100 to $150 each, and you need at least two: one before starting supplementation and one after 30 to 60 days. That's $200 to $300 in testing costs. Worth it if you're spending $200/month on the sachet and want confirmation. Probably overkill if you're just taking 250 mg of standalone NMN.

When to test your NAD+ levels

Take your baseline test before you start any NAD+ precursor. If you're already taking NMN, NR, or niacin, the baseline is gone. You can still test, but you'll only get a snapshot of your current levels without knowing where you started.

For the follow-up, 30 days is the minimum. Most NAD+ increases stabilize within two to four weeks of consistent supplementation. I'd recommend 60 days if you can wait, because it accounts for fluctuation in the first few weeks as your body adjusts.

Take both tests at the same time of day, under similar conditions (fasted vs. fed, time since last supplement dose). NAD+ levels fluctuate with circadian rhythm and food intake. Consistency in testing conditions makes the comparison meaningful.

How to interpret your NAD+ test results

There's no universally agreed "optimal" NAD+ level. The ranges depend on the test methodology. Both DoNotAge and Jinfiniti provide reference ranges with their results.

What matters more than the absolute number is the delta. If your pre-supplementation level is 30 (arbitrary units) and your post-supplementation level is 53, that's a 76% increase. That tells you the intervention is working regardless of whether 53 is "optimal" by some standard.

DoNotAge's clinical trial showed a mean 76% increase. If your personal increase is in that ballpark, the product is doing what it claims. If you see a 10% bump or no change, you might need a higher dose, a different delivery method, or there could be an absorption issue worth investigating.

See also: NMN bioavailability: liposomal vs. capsule vs. powder

Beyond NAD+: other longevity biomarkers to track

NAD+ is one marker. For a complete picture of whether your longevity protocol is working, I'd also track homocysteine (should drop if TMG is working), hs-CRP (systemic inflammation), vitamin D serum levels, fasting insulin and HOMA-IR (metabolic health), and if you're committed, a biological age test like TruDiagnostic or GrimAge. That full panel tells a story that NAD+ alone can't.

See also: NAD+ levels by age: how fast they drop

Frequently asked questions